Vancomycin in infusion during vitrectomy in surgical treatment of acute postoperative and posttraumatic endophthalmitis

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Vancomycin in infusion during vitrectomy in surgical treatment of acute postoperative and posttraumatic endophthalmitis

BACKGROUND Endophthalmitis is potentially devastating intraocular inflammation following eye trauma or surgery. We describe the visual outcomes and causative pathogens in acute bacterial postoperative and posttraumatic endophthalmitis treated with immediate pars plana vitrectomy (PPV) with Vancomycin dissolved in the infusion fluid. METHODS Clinical records of consecutive 30 patients with pos...

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Diabetes and postoperative endophthalmitis in the endophthalmitis vitrectomy study.

OBJECTIVES To determine whether there was a different response to vitrectomy and tap/biopsy with or without systemic antibiotic treatment in the Endophthalmitis Vitrectomy Study and whether the signs and symptoms of endophthalmitis differ between diabetic and nondiabetic patients. DESIGN A multicenter clinical trial in which patients with acute post-cataract extraction endophthalmitis were ra...

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Intravitreal vancomycin and gentamicin concentrations in patients with postoperative endophthalmitis.

BACKGROUND/AIMS To study the intravitreal antibiotic concentrations and the efficacy of an intravitreal dosing regimen to treat patients with postoperative bacterial endophthalmitis. This regimen, based on pharmacokinetic/pharmacodynamic considerations, relies on a repeat antibiotic injection of a lower dose than is generally used. METHODS In consecutive patients with suspected postoperative ...

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ژورنال

عنوان ژورنال: BMC Infectious Diseases

سال: 2016

ISSN: 1471-2334

DOI: 10.1186/s12879-016-1830-6